11 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... leukemia (blood ... overt cytoplasmic granules ... #Auer #Rods #Acute ... promyelocytic #leukemia
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... diagnosed with acute ... (APL) following ... decreased secondary granules ... also described in acute
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... ALL (Acute Lymphoblastic ... (Acute Myeloid ... (Acute Promyelocytic ... distinctive primary granules
Presentation of malignant disease in children 
Pre-school (<5 years old) 
 - Acute lymphoblastic leukaemia
years old) - Acute ... lymphoblastic leukaemia ... School-aged - Acute ... Adolescence - Acute ... Malignant #Childhood #Peds
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... are typical for acute ... myelogenous leukemia ... (AML) that is most ... Rods #AuerRods #AML
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Disorders • Acute ... (ALL) • Acute ... Myeloid Leukemia ... Hyperuricemia #Differential
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... histamine in their granules ... translocation • Acute ... thrombocythemia • Acute ... #Basophilia #Differential
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Standard-Risk Acute ... Lymphoblastic Leukemia ... Cytarabine #ALL ... #Leukemia #Treatment ... oncology #pediatrics #peds
The hematopoietic tree and the resulting leukemias and lymphomas 
The hematopoietic tree refers to the hierarchical
the resulting leukemias ... self-renew and differentiate ... into all types ... classified into acute ... Acute leukemias
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... Pleural effusions • Acute ... Antiribosomal P, APLA ... Hodgkin lymphoma and leukemia