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diagnosis management algorithm liver differential hematology injury evidence indications oncology 1 aclf acute albumin anemia aplastic bleeding calling cdi cdiff
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... #ACLF #Acute #Chronic ... #Hepatology #gastroenterology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... kg 3rd day with antibiotics ... Indications #Management #Cirrhosis ... #treatment #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
normal - Infection (EBV ... CMV), Alcoholic cirrhosis ... 5-10x normal - Chronic ... Liver #Injury #hepatology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Gl History - Cirrhosis ... current MELD - Chronic ... Calling #Referral #Hepatology ... #Gastroenterology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... treat the pts with chronic ... viremia or have cirrhosis ... Diagnosis #Management #Treatment ... #Hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... Rebound effect from treatment ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
Prevalence: At cirrhosis ... noxious stimuli) TREATMENT ... Initiate empiric treatment ... non-absorbable antibiotic ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HBV, HCV, HEV, EBV ... dechallenge • Acute or chronic ... e.g. ascites), Chronic ... Diagnosis #Algorithm #hepatology
Preventing Decompensation in Cirrhosis cACLD, CSPH, and the Rule of Five Prevention of Decompensation Nonselective Beta Blockers (NSBB) Preventing
Decompensation in Cirrhosis ... Decompensation #Cirrhosis ... #Prevention #treatment ... #management #hepatology ... #gastroenterology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... - β-lactam antibiotics ... Parvovirus B19 - EBV ... aplastic anemia Treatment ... Anemia #oncology #hematology
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