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cardiology diagnosis differential causes classes hyperkalemia medications antiarrhythmic antiarrhythmics summary algorithm comparison digoxin druginduced effects high hypokalemia impaired lactated low
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Transcellular Shift ... Algorithm #causes #potassium ... #low #pathophysiology
Antiarrhythmic Drugs CLASS IA • Procainamide, Quinidine, Disopyramide CLASS 1B • Lidocaine, Mexiletine CLASS 2 • Propranolol, Esmolol CLASS 4
Adenosine, Magnesium, Potassium ... Medications #Classes #Classification ... #Pharmacology #
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table Class I agents - Sodium Channel Blockers⠀ Class II
Vaughan Williams Classification ... Class III agents - Potassium ... #Medications #Classification ... Summary #Table #pharmacology
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... the cell, serum potassium ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... repolarization CLASS 3 - Potassium ... Vaughan #Williams #Pharmacology ... #Classification ... #Classes #pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Monitor potassium
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Vaughan Williams Classification ... repolarization CLASS 3 - Potassium ... #Classification ... #Classes #pathophysiology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... transcellular shift ... NS #comparison #pharmacology
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