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diagnosis erythematosus hematology lupus sle causes hemolytic management signs symptoms vasculitis workup autoantibodies autoimmune cardiology chronic classification cll disease hemeonc
Systolic Murmurs - Differential Diagnosis Algorithm Benign / Flow / Hyperdynamic: • Pregnancy • Fever • Anemia Supravalvular
Systolic Murmurs ... - Differential ... Diagnosis Algorithm ... • Anemia Supravalvular ... • Marfan's Disease
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential ... Diagnosis Algorithm ... malignancy, autoimmune disease ... HTN) • Recent travel ... /Fevers, DAT (-)
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... - Hemolytic anemia ... autoantibodies #signs ... #rheumatology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... schistosomiasis • Pyemia ... falls (like a wave ... Brucellosis Faget's Sign ... #Patterns #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... bartonella (oroya fever ... #workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Coronary arteries - Fever ... Vasculitis: • Fevers ... purpura: strong sign ... #diagnosis #rheumatology
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... old on day ≥7 of fever ... if evidence of systemic ... Albumin ≤3.0 g/dL, anemia ... clinical and lab signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Vasculitis: • Fevers ... purpura: Strong sign ... #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... to: Arthritis, Fever
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