26 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... mountain spotted fever ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Vasculitides, ... IBD, Celiac disease ... Diagnosis #Algorithm #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... #skin #rashes #differential ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Fevers • ... purpura: strong sign ... pulses, bruis, or blood ... Large Vessel: Blood ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... reticularis Differential ... (inflamed blood ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... , recurrent fevers ... , vasculitis • ... including peripheral blood ... Autoinflammatory #Somatic #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... purpura: Strong sign ... pulses, bruits, or blood ... #Rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... cardiac valve, vasculitis ... bartonella (oroya fever ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Rheumatic fever ... , Vasculitis (e.g ... arteritis • Bloody ... #joint #pain #differential ... #diagnosis #rheumatology