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diagnosis symptoms management erythematosus headache infections lupus neurology sle systemic disease msk syndrome vasculitis activation algorithm antimda5 antimda5dm autoantibodies autoimmune
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
• Meningeal signs ... Systemic symptoms and signs ... (e.g., fever, myalgia ... brain lesion • CNS ... ) • Temporal arteritis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
myocarditis, coronary arteritis ... SLE, Reactive arthritis ... Ocular melanoma • Arthritis ... SLE, Reactive Arthritis ... diagnosis #management #signs
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
to Joint Pain - Arthritis ... noninflammatory Signs ... • Reactive arthritis ... • Lyme arthritis ... #Arthritis #
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Juvenile idiopathic arthritis ... • Rheumatoid arthritis ... falls (like a wave ... Brucellosis Faget's Sign
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: Fever ... of hip (rare), Arthritis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
Early and Late Clinical ... arthralgia, headache, fever ... lymphocytic meningitis, CN ... years after • Arthritis ... Disease #diagnosis #signs
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Malar rash 40% - Fever ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... ) Giant cell arteritis ... systemic sx + signs ... versus Temporal Arteritis ... GCA #Temporal #Signs
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... is the main clinical ... nervous system (CNS ... juvenile idiopathic arthritis ... #Rheumatology
13 Dangerous Causes of Headache: - subarachnoid hemorrhage: family history, PCKD, known berry aneurysm, sudden and
hypertension - CNS ... infection: fever ... temporal (giant cell) arteritis ... thrombophilia, neurologic signs ... Dangerous #Deadly #Differential
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