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differential hemeonc management autoimmune cardiology ecg electrocardiogram emergencies hemophagocytic hlh leukostasis lymphohistiocytosis myopathy myositis oncologic oncology rheumatology stemi tls tumor
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Origin (FUO) - ... Workup • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... #workup #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... unless worrisome EKG ... #diagnosis #management ... #hematology
STEMI Equivalents on ECG • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
STEMI Equivalents ... J point • De Winter ... syndrome - J-point ... V2 • Wellens sign ... #ECG #EKG #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... TLS (tumor-lysis ... syndrome): - Hematologic ... Oncology #HemeOnc #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... Presentation • Common Signs ... and Symptoms: ... Fever b. ... #Management #Hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... papules and Gottron sign ... ) • Shawl sign ... : Fever, joint pain ... : • Fever • Interstitial
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