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rheumatology differential erythematosus lupus management sle systemic vasculitis autoimmune cardiology classification ecg electrocardiogram hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis myopathy
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Origin (FUO) - ... Workup • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... #workup #diagnosis
STEMI Equivalents on ECG • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
STEMI Equivalents ... J point • De Winter ... syndrome - J-point ... V2 • Wellens sign ... #ECG #EKG #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Differential Diagnosis ... Induced Lupus: • Symptoms ... to: Arthritis, Fever ... Erythematosus #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... Presentation - Systemic Symptoms ... Vasculitis: • Fevers ... purpura: strong sign ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... papules and Gottron sign ... ) • Shawl sign ... : Fever, joint pain ... : • Fever • Interstitial
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... Presentation • Common Signs ... and Symptoms: ... Fever b. ... #Management #Hematology
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