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differential rheumatology signs ana antinuclear erythematosus pathophysiology sle syndrome systemic vasculitis arthritis autoantibodies autoimmune classification dermatology emergency fever headache infections
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... context of other symptoms ... Arthritis, Sjögren ... #rheumatology #diagnosis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... Juvenile Idiopathic Arthritis ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... : - Arthritis ... SLE-Related Auto-Antibodies ... autoantibodies #signs ... #symptoms #mimickers
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
diseases like rheumatoid ... arthritis (RA) ... or systemic lupus ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
< 30 years - Aorta ... : Systemic rheumatic ... Presentation - Systemic Symptoms ... purpura: strong sign ... : antibodies directed
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... • Is there a pattern ... noninflammatory Signs ... constitutional symptoms ... an asymmetric pattern
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... ANCA-associated vasculitis, rheumatoid ... : • Symptoms limited ... 1, SCL-70, RNP antibodies ... Erythematosus #Diagnosis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... characteristic antibodies ... Peptide (aCCP), Rheumatoid ... Extra-articular signs ... #symptoms #diagnosis
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Still's disease • Rheumatoid ... arthritis • Crohn's ... falls (like a wave ... Brucellosis Faget's Sign
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... development of skin symptoms ... - Neutrophilic rheumatoid ... ’s syndrome - Lupus
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