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differential obstetrics pregnancy treatment comparison hemolysis obgyn rheumatology table thrombocytopenia ttphus anemia causes chronic common cvid extravascular fatty gout hemolytic
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Syndrome and Acute ... of Pregnancy (AFLP ... ) Three syndromes ... the critically ill ... #hematology #diagnosis
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... the critically ill ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... TTP, HUS, DIC, HELLP ... Drug-associated, PCH, Evans Syndrome ... : Sickle cell anemia ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... syndrome - ... ) (e.g. lupus, CLL ... #hematology #anemia
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Pathophysiology: • Defect ... ↓Antithrombin Ill ... Preeclampsia, HELLP ... iMedEducation #AFLP
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... Physical Exam/Signs ... Diagnosis: • ... • Richter’s Syndrome ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... : HLH signs and ... #management #treatment ... #hematology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... Multiple Sclerosis Diagnosis ... resonance imaging [MRI ... #management #neurology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Affects 1:25,000 ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... CRP GCA (Giant Cell ... oligoclonal bands • MRI ... #Rheumatology
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