25 results
Summary table of mechanism of action, side effect and contraindications of commonly used diabetic drugs. 

#pharmacology
Summary table of ... of action, side effect ... commonly used diabetic ... #pharmacology #dm2 ... #diabetes #medications
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... failure Common Side Effects ... definitively cause/effect ... #Pharmacology # ... Summary #DM2 #diabetes
Cardiovascular and renal effects comparison between SGLT-2 inhibitors
 - Canagliflozin (Invokana)
 - Dapagliflozin (Farxiga)
 - Empagliflozin
Cardiovascular and renal effects ... between SGLT-2 inhibitors ... (Steglatro) #diabetes ... renal #SGLT2i #Inhibitors ... #pharmacology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... ) Common Side Effects ... • Euglycemic diabetic ... #Pharmacology # ... Summary #DM2 #diabetes
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Electrolyte Excretion Effects ... Carbonic Anhydrase Inhibitor ... #electrolytes #effects ... #pharmacology # ... comparison #table
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... drugs include side effects ... Side effects include ... #Pharmacology # ... Medications #DM2
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
Effects on body ... classes of type-2 diabetes ... Loss + - SGLT-2 inhibitors ... Loss +++ - DPP-4 inhibitors ... weightgain #comparison #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... disease Common Side Effects ... Toxicities: • GI side effects ... #Metformin #Pharmacology ... diabetes #endocrinology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Treatment for Diabetes ... gastrointestinal (GI) adverse effects ... Indications #Titration #Pharmacology ... #Diabetes #DM2
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology