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endocrinology summary dpp4 medications sglt2 agonists anthracycline cardiology cardiotoxicity causes chemotherapy classification comparison diagnosis differential dosing electrolytes glp1 her2 hypomagnesemia
Diuretic Electrolyte Excretion Effects Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid - Thiazide Type
Excretion Effects ... Diuresis, Na+, ... Carbonic Anhydrase Inhibitor ... #effects #pharmacology ... #comparison #table
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Mechanism of Action, Effects ... CARBONIC ANHYDRASE INHIBITORS ... others SGLT2 INHIBITORS ... #Medications #Pharmacology ... #summary #table
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... failure Common Side Effects ... definitively cause/effect ... #Pharmacology # ... Summary #DM2 #diabetes
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... leading to osmotic diuresis ... ) Common Side Effects ... #Pharmacology # ... Summary #DM2 #diabetes
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
drugs include side effects ... are similar to diuretics ... Side effects include ... #Pharmacology # ... Medications #DM2
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
- Proton-pump inhibitors ... - Calcineurin inhibitors ... - Uncontrolled diabetes ... - Genetic defects ... Low #Magnesium #Table
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... #Summary #DM2 # ... diabetes #endocrinology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
system (RAAS) inhibitor ... antagonist (MRA) plus diuretic ... hypertension, diabetes ... monitoring to detect ... cardiology #oncology #pharmacology
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