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comparison diabetes dm2 medications management summary dpp4 glp1 inhibitors treatment acromegaly antifungals binders binding buprenorphine cardiology cholinergic coccidioides coccidioidomycosis ddi
Opioid Use Disorder Medications - Pharmacokinetics Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects ... #Pharmacology #
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... DM2 #diabetes #endocrinology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... DM2 #diabetes #endocrinology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
GLP-1 Agonists ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... Diabetes #DM2 #Endocrinology
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #comparison #table
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
15 g QD • Side Effects ... 8.4 g • Side Effects ... daily • Side Effects ... #medications #pharmacology ... #table #comparison
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
Dosing: 3 mg ... drug to remain stable ... upset as a side effect ... semaglutide #Diabetes #Pharmacology ... #Endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... titrate up to effects ... only few side effects ... #Pharmacology # ... Diabetes #DM2 #Endocrinology
Summary of actions of some Cholinergic Agonists Bethanechol • Used in treatment of urinary retention • Binds
some Cholinergic Agonists ... CNS and cardiac effects ... • Reverses CNS effects ... #Pharmacology # ... Table #Summary
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products Angiotensin-Converting Enzyme Inhibitors (ACEIs) • Night-blooming
cereus - Increases effects ... Decreases the effects ... Bilberry, Danshen, Dong ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
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