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diabetes dm2 summary glp1 inhibitors cholinergic management oral receptor renal rybelsus semaglutide
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... DM2 #diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... titrate up to effects ... only few side effects ... #Pharmacology # ... Diabetes #DM2 #Endocrinology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
to the incretin effect ... Common side effects ... very similar to DPP4s ... #Pharmacology #Dosing ... Diabetes #DM2 #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... DM2 #diabetes #endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
Dosing: 3 mg ... drug to remain stable ... empagliflozin and DPP4 ... semaglutide #Diabetes #Pharmacology ... #Endocrinology
Summary of actions of some Cholinergic Agonists Bethanechol • Used in treatment of urinary retention • Binds
some Cholinergic Agonists ... CNS and cardiac effects ... • Reverses CNS effects ... #Pharmacology # ... Table #Summary
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