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diabetes diagnosis dm2 summary comparison glp1 management medications acromegaly buprenorphine cholinergic dpp4 drugs hepatology hypertension hypnotic inhibitors methadone naltrexone nerveagents
Opioid Use Disorder Medications - Pharmacokinetics Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... euphoric effects ... to block their effects
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... #Agonists #Pharmacology
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #comparison #table
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... therapy with GLP-I receptor ... agonist • Personal ... failure Common Side Effects ... DM2 #diabetes #endocrinology
Nerve agent exposure is a generalized whole-body exposure. Similar to organophosphates, symptoms and signs result from
, symptoms and signs ... Acetylcholine exerts its effects ... and muscarinic receptors ... than muscarinic effects ... SignsSymptoms #Table
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
GLP-1 Agonists ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... Diabetes #DM2 #Endocrinology
Portopulmonary Hypertension Presence of pulmonary arterial hypertension in a patient with portal hypertension No other obvious causes (chronic
regurgitant velocity using ... m/s • Other signs ... of endothelin receptors ... the vasodilatory effects ... stimualtes sGC receptors
Summary of actions of some Cholinergic Agonists Bethanechol • Used in treatment of urinary retention • Binds
some Cholinergic Agonists ... CNS and cardiac effects ... • Reverses CNS effects ... #Pharmacology # ... Table #Summary
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
Dosing: 3 mg ... drug to remain stable ... upset as a side effect ... semaglutide #Diabetes #Pharmacology ... #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Macroadenoma direct effects ... multisystemic anabolic effects ... Lanreotide) ± GH receptor ... Pegvisomant) ± D2 agonist ... Diagnosis #Management #Endocrinology
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