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endocrinology dm2 comparison glp1 summary anxiety buprenorphine depression disorders dosing dpp4 drugs glftap hypnotic inhibitors macroadenoma management masseffects methadone mnemonic
Opioid Use Disorder Medications - Pharmacokinetics Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects ... #Pharmacology #
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... Summary #DM2 #diabetes
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... #Diabetes #DM2
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... #Summary #DM2 #diabetes
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #pharmacology #
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
semaglutide, the same medication ... drug to remain stable ... upset as a side effect ... #semaglutide #Diabetes ... #Pharmacology #
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... less common and affect ... targeted with medication ... Signs / Symptoms ... Hyperprolactinemia • Diabetes
Drugs for Depression and Anxiety Disorders Selective Serotonin Reuptake Inhibitors • Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline,
selective; little effect ... 5HTIA partial agonist ... PTSD, menopause symptoms ... Anxiety #Disorders #Medications ... #Table #Pharmacology
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