7 results
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects ... #Pharmacology #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... Summary #DM2 #diabetes
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... #Summary #DM2 #
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
commonly used medications ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... #Diabetes #DM2
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #pharmacology #
Drugs for Depression and Anxiety Disorders

Selective Serotonin Reuptake Inhibitors
 • Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline,
selective; little effect ... 5HTIA partial agonist ... PTSD, menopause symptoms ... Anxiety #Disorders #Medications ... #Table #Pharmacology
Nuclear myocardial perfusion imaging (MPI) may be performed by either single-photon emission CT (SPECT) or positron
Pharmacologic stress ... valve area <1.0 cm2 ... and have ongoing symptoms ... adenosine receptor agonists ... undesirable adverse effects