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diabetes endocrinology comparison summary dpp4 glp1 inhibitors management adenosine anxiety binders binding buprenorphine cardiacstresstest cholinergic coronarystenosis depression disorders drugs hyperkalemia
Opioid Use Disorder Medications - Pharmacokinetics Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects ... #Pharmacology #
Metformin - First Line Treatment for Diabetes Type 2 • Start with initial dose of 500 mg
gastrointestinal (GI) adverse effects ... form and consider using ... than stopping medication ... #Titration #Pharmacology ... #Diabetes #DM2
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... Summary #DM2 #diabetes
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
commonly used medications ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... #Diabetes #DM2
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... #Summary #DM2 #
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #pharmacology #
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... titrate up to effects ... only few side effects ... #Pharmacology # ... Management #Diabetes #DM2
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
15 g QD • Side Effects ... 8.4 g • Side Effects ... daily • Side Effects ... #pharmacology # ... table #comparison
Review of Intranasally Administered Medications for Use in the Emergency Department Table of agents, uses, dosing, onset
Emergency Department Table ... agents, uses, dosing ... and major side effects ... #Comparison #Table ... #Pharmacology #
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
Dosing: 3 mg ... semaglutide, the same medication ... drug to remain stable ... upset as a side effect ... semaglutide #Diabetes #Pharmacology
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