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diabetes summary inhibitors dosing agonists glp1 medications sglt2 based combo comparison estimation inpatient insulin management mellitus metformin oral pills receptor
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
Diabetes Combination ... Metformin + DPP4 ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... Recommended to avoid combination ... failure Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... Management #Diabetes #DM2 ... #Endocrinology
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... disease Common Side Effects ... #Metformin #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Sulfonylureas - Pharmacology Summary Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... CKD Common Side Effects ... Sulfonylureas #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... ) Common Side Effects ... SGLT2 #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
Common side effects ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... Dosing #Diabetes #DM2 ... #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... Diabetes #Mellitus #DM2 ... #Medications #pharmacology ... comparison #table #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Toxicities: • Gl side effects ... Receptor #Agonists #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing TDD in units of insulin = N
glucocorticoids, or combination ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
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