15 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + DPP4 ... Metformin + SGLT2 ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 #Pharmacology ... #Pills #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... Summary Mechanisms ... failure Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Medications • SGLT2i ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications Summary ... events TZDs DPP ... -4 inhibitors SGLT2 ... comparison #management #endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... Summary Mechanisms ... ) Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Mechanism of Action, Effects ... Acetazolamide, others SGLT2 ... #Medications #Pharmacology ... #summary #table
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
Effects on body ... Weight Loss + - SGLT ... Weight Loss +++ - DPP ... weightgain #comparison #pharmacology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Summary Mechanisms ... CKD Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... /ambcarerx #SGLT2 ... #Inhibitors #Pharmacology ... DM2 #Diabetes #Endocrinology