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diagnosis differential signs neurology sclerosis systemic vasculitis aion algorithm ana anteriorischemicopticneuropathy antibodies antinuclear classification erythematosus gca giantcellarteritis lupus management manifestations
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Motor and sensory deficits ... positive NMO only): Myositis ... , Comorbid autoimmune ... diagnosis #neurology #symptoms ... #signs
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... and Symptoms: ... acro-osteolysis, myositis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Restrictive lung defect ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
field: altitudinal defect ... • Cephalic symptoms ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Sclerosis (MS) is an autoimmune-mediated ... neuritis • Partial myelitis ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... Signs and symptoms
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
technique used to detect ... Positive ANA ≠ Autoimmune ... context of other symptoms ... Sjögren Syndrome, Myositis ... ANA #patterns #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... Conjunctivitis, mucositis ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vasculitis) - Affects ... Conjunctivitis, mucositis ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
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