19 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Afferent pupillary defect ... SIGNS/SYMPTOMS ... Signs and symptoms ... Treatment: • ... #diagnosis #management
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... megaloblastic anemia Treatment ... Anemia #diagnosis #management ... #treatment #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... When present, symptoms ... , signs, and complications ... PV #Diagnosis #Management ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Classic - Nodular Sclerosis ... pattern of spread, B symptoms ... Responsive to Treatment ... pathophysiology #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
most frequently affects ... Diagnosis: HLH signs ... and symptoms can ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral Sclerosis ... fasciculations Common Symptoms ... conditions listed in differential ... diagnosis column Treatment ... neurology #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... workup #oncology #hematology