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diagnosis management hematology signs erythematosus lupus oncology systemic autoimmune classification leukemia myositis neurology vasculitis acidosis acute algorithm ana antibodies antinuclear
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Restrictive lung defect ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Wernicke-Korsakoff syndrome ... , neural tube defects ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Associated - SLE ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... anti-synthetase syndrome ... Can also see mechanics ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Signs and Symptoms Associated With Different Headache Etiologies • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... vasoconstriction syndrome ... #headache #signs ... #symptoms #clues ... #differential #
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... enzymes ↑ • Mild anemia ... • New onset SLE ... antibody test) Treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behcet disease) Differential ... Oral aphthae : SLE ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Paraneoplastic effects ... rheumatoid arthritis, SLE ... life-threatening Differential ... test - Cogan sign ... - Peek sign
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment
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