18 results
rheumatology differential signs symptoms treatment hemophagocytic hlh lymphohistiocytosis aflp aids algorithm apml associated autoimmune behcet cerebritis dementia differentiation disease disorder
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... #neurology #rheumatology ... #management #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
- Differential Diagnosis ... papilledema • Horner syndrome ... • Neurological deficits ... brain lesion • CNS ... #Algorithm #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Motor and sensory deficits ... pain • Extra-CNS ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... : • Defect in fetal ... AP, ↑INR, ↑BUN/Cr ... ) Differential Diagnosis ... #management #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... common • Imaging: CXR ... Differentiation #Syndrome ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
the posterior occipital ... may precede the neurologic ... Etiology: • Pathophysiology ... #diagnosis #management ... #neurology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... Multiple Sclerosis Diagnosis ... objective evidence of neurologic ... #management #neurology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... : HLH signs and ... #management #treatment ... #hematology
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