13 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... failure Common Side Effects ... #Inhibitors #Pharmacology ... #Summary #DM2 #diabetes
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... titrate up to effects ... only few side effects ... #Dosing #Pharmacology ... #Management #Diabetes
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
Effects on body ... classes of type-2 diabetes ... Weight Loss +++ - DPP ... -4 inhibitors - ... weightgain #comparison #pharmacology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... include side effects ... Side effects include ... #Pharmacology # ... Medications #DM2 #Diabetes
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Agents Subclass, Drug ... Mechanism of Action, Effects ... others SGLT2 INHIBITORS ... #Medications #Pharmacology ... #summary #table
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Cardiovascular Drug-Drug ... Angiotensin-Converting Enzyme Inhibitors ... Monoamine Oxidase Inhibitors ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... Common side effects ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
regurgitant velocity using ... m/s • Other signs ... Pulmonary artery diameter ... Phosphodiesterase-5 inhibitors ... the vasodilatory effects
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
oral suspension DOSING ... with CKD, HF, or diabetes ... ACE inhibitors, ... Most common side effect ... #Hyperkalemia #Pharmacology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... to remain stable ... empagliflozin and DPP4 ... #semaglutide #Diabetes ... #Pharmacology #