23 results
Cardiovascular and renal effects comparison between SGLT-2 inhibitors
 - Canagliflozin (Invokana)
 - Dapagliflozin (Farxiga)
 - Empagliflozin
Cardiovascular and renal ... effects comparison ... between SGLT-2 inhibitors ... (Steglatro) #diabetes ... #pharmacology
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Electrolyte Excretion Effects ... Epithelial Sodium Channel ... #electrolytes #effects ... #pharmacology # ... comparison #table
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
Effects on body ... classes of type-2 diabetes ... Loss + - SGLT-2 inhibitors ... Loss +++ - DPP-4 inhibitors ... weightgain #comparison #pharmacology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... Epithelial Cells Renal ... ATPase Nephrogenic diabetes ... Epithelial #Inherited #Defects ... #Differential #Table
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics - Sodium Channel ... Subclasses, Mechanisms, Indications ... , Side Effects la ... Na #cardiology #pharmacology ... #table #comparison
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
has very minimal chance ... titrate up to effects ... only few side effects ... #Pharmacology #Management ... #Diabetes #DM2
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... failure Common Side Effects ... definitively cause/effect ... #Pharmacology # ... Summary #DM2 #diabetes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Proton-pump inhibitors ... Loses - Medications ... - Uncontrolled diabetes ... - Genetic defects ... Low #Magnesium #Table
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... Mechanisms and Side Effects ... - Cognitive Changes ... Pathophysiology #Pharmacology ... Psychiatry #Diagnosis #Signs
Dihydropyridine Calcium Channel Blockers

Mechanism of Action:  L-Type calcium channel blockade - Inhibits the influx of
L-Type calcium channel ... blockade - Inhibits ... vasodilation Indications ... hypertension Side Effects ... Blockers #CCB #pharmacology