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diagnosis differential erythematosus lupus signs autoimmune vasculitis ana antibodies antinuclear autoantibodies chronic classification cll hematology leukemia lymphocytic mimickers myopathy oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Restrictive lung defect ... Glomerulonephritis Myositis ... #signs #symptoms ... #diagnosis #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... , holster sign, ... Can also see mechanics ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
(SLE) - Typical ... Signs/Symptoms ... Arthralgia / arthritis, Myositis ... #Signs #Symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
technique used to detect ... context of other symptoms ... erythematosus (SLE ... Sjögren Syndrome, Myositis ... ANA #patterns #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... purpura: Strong sign ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vasculitis) - Affects ... Symptoms (Sx) in ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... • M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... ’s CLL Scoring system
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... #Myopathy #rheumatology
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