21 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Pulmonary Thromboendarterectomy
Chronic Thromboembolic Pulmonary Hypertension
Definition: mean pulmonary-artery pressure > 25mmHg
Thromboembolic Pulmonary ... embolism Pathophysiology ... multiple bilateral defects ... Bypass Other Treatment ... Thromboendarterectomy #diagnosis #management
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, knees ... , shoulders Signs ... exam and imaging Treatment ... Arthritis #diagnosis #management ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... initiation • Differential ... APML #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Paraneoplastic effects ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... Lung Abscess Pathophysiology ... Lung Abscess Differential ... Lung #Abscess #pulmonary ... #differential #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
most frequently affects ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Diagnosis and Management ... malignancy Pathophysiology ... Differential Diagnosis ... Endocrinology #Treatment ... #Pathophysiology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
Hypertension Presence of pulmonary ... m/s • Other signs ... pressure < 15mmHg TREATMENT ... the vasodilatory effects ... Hypertension #diagnosis #management