23 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
elbows/wrists and knees ... skin thickening Signs ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... effusion, Restrictive lung ... defect (rare) Raynaud's ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... : • Most common ... Physical Exam/Signs ... Scoring system: ... workup #oncology #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Pain in Sickle Cell ... long bones ... • Most common ... • Differentiate ... diagnosis #causes #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
definition: Most common ... sx + signs/sx of ... very remarkable w/differential ... them, but urgent rheumatology ... GCA #Temporal #Signs
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
Diagnosis The most common ... shifting dullness detect ... dullness, puddle sign ... incisional). 3) Signs ... Routine tests: Cell
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... mass and NO prior signs ... Differential diagnosis ... • PVNS/Giant Cell ... diagnosis #msk #rheumatology
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
cancerous cells from systemic ... 200 times more common ... • Lung. thvroid ... Signs/Symptoms: ... BoneTumors #Malignant #Radiology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Affects 1:25,000 ... • Chronic lung ... hemolytic anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology