33 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
flexion of the knees ... Passive neck flexion causes ... While the pathophysiology ... for the hip/knee ... is that hip and knee
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... lymph -> Koplik's spots ... cataracts, cardiac defects ... direct contact & infects ... peds #pediatrics #pathophysiology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Mechanisms and Side Effects ... Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... Psychiatry #Diagnosis #Signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Mechanisms and Side Effects ... Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... Psychiatry #Diagnosis #Signs
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... scapularis • Infects ... within morulae Signs ... is rare (< 10% cases ... ), cough (30% cases
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... diabetes Key signs ... hypotension) DKA: Short
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis #signs
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
capillaries • Criteria ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs ... • Pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Valgus position of knee ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Lhermitte’s sign ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... McDonald diagnostic criteria ... taper 3-7 days - Short