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diagnosis differential management causes hyperkalemia pathophysiology antiarrhythmics cardiology classes hematology pharmacology rheumatology treatment acidosis addisons adrenal amyloid amyloidosis blood clinicopathology
Hypokalemia - Differential Diagnosis Poor Intake - Starvation - Anorexia GI Losses - Vomiting / NG
and 2, but not type ... Alkalosis - Marked cell ... Differential #Diagnosis #Low ... #Potassium #Table ... #Classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... ~90% • Low Grade ... #Classification ... #differential #algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
hematological disorders ... to Autoimmune Disorders ... • Cryocrit - Detect ... factor level • Low ... #classification
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... channel blocking effects ... repolarization CLASS 3 - Potassium ... ++ influx into cells ... #Pharmacology #Classification
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Infiltrative Disorders ... cancer • Renal cell ... NAGMA from RTA type ... • Weakness • Low-grade ... Check sodium, potassium
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... channel blocking effects ... repolarization CLASS 3 - Potassium ... ++ influx into cells
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... LV failure - Low ... B3: Hereditary Defects ... myopathies - Defects ... #typeb #classification
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Hereditary defects ... l; defects in the ... Drug-associated: heparin, low-molecular-weight ... Diagnosis #High #Potassium ... #Classification
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Summary Group of disorders ... fibrils formed from low-molecular-weight ... configuration Types ... Proteinuria • Can detect ... Cardiac: • LVH, low-voltage
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Aldosterone, RTA Type ... Elimination (see Table ... acidosis) • Low ... Drives K+ into cells ... Management #Treatment #potassium
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