10 results
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hodgkin's Lymphoma ... Hodgkin's Lymphoma ... translocation • Types: Classification ... , Hodgkin Lymphomas ... #differential #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia (sometimes) Macrocytic ... Unstable hemoglobin disorders ... Cell Agglutinate: Cold ... , Malignant lymphoma ... differential #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... ingestion • B symptoms ... number of sites of disease ... #hematology #oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
e.g. lupus, CLL, lymphoma ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... lymphoproliferative disorders ... differential #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Hodgkin Lymphoma ... pattern of spread, B symptoms ... #Classification ... pathophysiology #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... symptoms - most ... Monoclonal IgM Includes Disorders ... #hematology #diagnosis
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Differential Diagnosis Algorithm ... Malignant • Lymphoma ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Agglutination - Cold ... Consider RBC membrane disorder ... Differential #Diagnosis #Algorithm ... #workup #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... with no early symptoms ... cells can indicate disease ... lymphoproliferative disorders ... workup #oncology #hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... experience some symptoms ... MCV 80-100 fl) & macrocytic ... that involves disorders ... These causes could