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diagnosis management oncology syndrome algorithm comparison dermatomyositis differential druginduced eosinophils hes hypereosinophilia lupus table anemia anticoagulation antimda5 antimda5dm antinxp2 antinxp2dm
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Hypereosinophilic Syndrome • Clinically ... Diagnosis and Treatment ... Syndrome #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... (common causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
than 1500 and clinical ... attributable to eosinophilia ... with blood eosinophilia ... Secondary Causes ... #diagnosis #hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
validated for VTE treatment ... studies suggest net clinical ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... involvement (2%) Cutaneous ... Treat primary cause ... #treatment #management ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis: • Clinical ... → Calculate 4T score ... • If 4T score ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Rare (SSA+ for cutaneous ... rare), Topics for cutaneous-DIL ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... auricular papules Clinical ... Men • ~50% of cases ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP Score ... -> AML: Blast crises ... • (Peripheral eosinophilia ... violaceous, nontender cutaneous ... #Leukemia #Hematology
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