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diagnosis causes algorithm elevatedmcv macrocytosis rheumatology secondary systemic workup approach arthritis atlas bloodcell calculation classification deficiency dermatology disease erythematosus fatigue
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... Amy Chung, MD, MSc ... #Disorders #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm Blood ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Chemotherapy (e.g ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... blood loss), Vitamin ... deficiencies: Chronic ... Production #Index #hematology ... #anemia #differential
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... inflammatory disorders ... (e.g. autoimmune ... Diagnosis #Causes #hematology
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Diet: ↓ Intake, e.g ... Inflammation: IBD, Chronic ... Iron metabolism disorders ... Deficiency #Causes #differential ... #diagnosis #anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Algorithm Normal Blood ... Increased Requirement (e.g ... • Small Bowel Disorder ... Algorithm #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Volume (MCV) - Differential ... Causes: Chronic ... Blood Loss, Occult ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue - Differential ... Neoplastic / Hematologic ... • Anemia • ... • Drug Abuse (e.g ... • Somatization Disorder
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... plateletcount), peripheral blood ... function test, ANA (e.g ... changes), high MCV anemia ... #Differential #
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