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Demyelinating Diseases - Differential Diagnosis • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE •
Demyelinating Diseases ... Polyarteritis nodosa, SLE ... Adrenoleukodystrophy #Demyelinating
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... lesions, Psychosis, Demyelinating ... Thrombocytopenia #Lupus #SLE
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Manifestations: Demyelinating ... Erythematosus #SLE
NPSLE - Neurological and Psychiatric Manifestations of Systemic Lupus Erythematosus • Central: Aseptic meningitis, Cerebrovascular disease,
Cerebrovascular disease, Demyelinating ... Erythematosus #SLE
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Demyelinating: ... Behcet disease - SLE
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Evaluate for NMO, SLE ... Etiologies: • Demyelination ... Disorders: - SLE
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... system (CNS): demyelinating
CNS Ring-Enhancing Lesions - Differential Diagnosis Framework Ring Completeness • Incomplete: Demyelinating Disease • Complete (MAGIC):
• Incomplete: Demyelinating
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
chronic inflammatory demyelinating
MAGIC DR – a handy mnemonic used to remember the potential causes of a cerebral ring
Contusion D – Demyelinating
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