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management differential hematology lupus oncology sle syndromes systemic signs vasculitis activation apml bee behcet chronic classification cll comparison differentiation disease
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... attributable to central ... and treatment can ... Systemic lupus erythematosus
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... systemic lupus erythematosus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Treatment: ... Systemic Lupus Erythematosus ... comparison #table #rheumatology ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... mononeuritis multiplex WORKUP ... o infection • Echocardiogram ... or serologies + symptoms ... #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : >3 symptoms, or ... Anaphylaxis, Acute Renal ... Failure Treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... #rheumatology #
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