11 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Clinical TLS: • AKI ... Intravenous fluids • Renal ... TLS #diagnosis #management ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... gammopathy of renal ... malignancies Treatment ... cyclophosphamide) #Acute ... #Cancer #Oncology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... : • Hypovolemia ... Abdominal Compartment Syndrome ... nephrology #causes #algorithm
Toluene Poisoning - Diagnosis and Management Summary
What is it?  Volatile hydrocarbon, Glue or paint-sniffing, Occupational
Diagnosis and Management ... associated with AKI ... chronic: • Marked hypokalaemia ... may be ↑ or ↓ Treatment ... #Treatment
Management of Acute Tubulointerstitial Nephritis (aka Acute Interstitial Nephritis). Simplified management algorithm for investigation and treatment
Management of Acute ... Tubulointerstitial Nephritis (aka ... algorithm for investigation ... and treatment of ... when to go for renal
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Compartment syndrome ... declines > ALT) • AKI ... + myoglobin AKI ... Differential #Diagnosis #Management
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... grade lymphoma & Acute ... #TLS #oncology ... #management #UricAcid
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
fever - ACS, AKI ... , acute limb ischemia ... organ damage • Treatment ... hydration - Hyperkalemia ... TLS #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure ... APML #diagnosis #management ... #hematology #oncology