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diagnosis pathophysiology differential spinalcord caudaequina management spinal syndromes acute algorithm alzheimersdisease bulimianervosa cauda dementia disorders equina geriatrics injury lesions ms
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Cord Syndrome - ... reflex. saddle ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... Cord Syndrome: ... in deep tendon reflexes ... ) Cord Syndrome:
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... / Symptoms / Complications ... of normal leg reflexes ... #MSK #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... / Symptoms / Complications ... seizure, primitive reflexes ... #symptoms
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... - Emergency Causes ... Diagnosis: • Spinal cord ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... Causes: 1. ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes ... disorders #diagnosis #neurology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... /SYMPTOMS: • CENTRAL ... Signs and symptoms ... (Spinal cord predominant ... objective evidence of neurologic
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... • Infectious causes ... diagnosis #management #neurology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... or the spinal cord ... pathophysiology #diagnosis #signs ... #symptoms #complications
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
inflammation -> Acid reflux ... • Boerhaave syndrome ... hormone levels cause ... pathophysiology #diagnosis #signs ... #symptoms #psychiatry
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