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differential sle treatment criticalcare erythematosus icu nephrology rhabdomyolysis summary systemic vasculitis agitation algorithm ana antibodies antibody antineutrophil antinuclear cardiology champs
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... • Sjögren syndrome ... polyangiitis without renal ... + 30-60% • Renal-limited ... #rheumatology #
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Antinuclear (ANA ... severe disease & renal ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... tract, and often causes ... such as systemic lupus ... • Urinalysis (Renal ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
• Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... S - Systemic Lupus ... Erythematosus (total 50, renal ... CHAMPS #Mnemonic #diagnosis
Hypermagnesemia - Etiologies by Mechanism Renal Failure Excessive Mg Administration - Massive PO intake
by Mechanism Renal ... - Tumor lysis syndrome ... #Differential #Diagnosis ... High #Magnesium #Table ... #Causes #Management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... hemorrhage (DAH) & renal ... pulmonary and renal ... BMP (quantify renal ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Erythematosus #Diagnosis ... #Rheumatology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
HYPOTENSION -> renal ... vasocontriction-> decreased renal ... renal ischemia ... Cast formation: Renal ... #causes #treatment
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