21 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... Primer Class I - ... DrFlashHeart #Lupus ... Nephritis #SLE #Classification ... #diagnosis #management
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... > 0.5 g/24 hr, Class ... , Class Ill or IV ... #EULARACR #Classification
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... BaillouChloe #Lupus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... thiazidic, PPI, ACE ... Positive in 60-80% of cases ... Usual therapeutic management ... rheumatology #diagnosis #management
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
Treatment Algorithm ... Nephritis (Class ... III/IV or Mixed Class ... #Treatment #Algorithm ... #Nephritis #management
A priority in this project was to appropriately stratify participants into a low, medium, or high-intensity
group-based exercise class ... The classification ... CDC, entitled “Algorithm ... The algorithm is ... STEADI) #Diagnosis #Management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... therapy to treat class ... #Membranous #Lupus ... #Treatment #management
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... CO • a (>10 mcg ... cAMP/cGMP • Causes ... Vasopressors #Inotropes #Pharmacology ... #Summary #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
• Special cases ... #rheumatology #pharmacology ... #levels #lupus ... #management
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Torsades de Pointes - Management ... Algorithm Drugs ... • Adult: 0.5-5 mcg ... TorsadesdePointes #TDP #Management ... #Algorithm