10 results
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... in a case of acute ... myeloid leukemia ... #AML #Clinical ... #Hematology #Pathology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... Diagnosis Algorithm ... • Epinephrine Cancer ... Diagnosis #Algorithm ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... -> AML: Blast crises ... Leukemia): • Neutrophils ... cutaneous plaques) AML ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... Infectious: • Acute ... disorders • Celiac ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Rhinitis - Allergic Dermatitis ... Primary: - CML ... Mastocytosis - Acute ... #Diagnosis #Causes ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... dermatosis Diagnosis ... Differentiation #Syndrome #APML ... #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Treated Like Acute ... Leukemias, very ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(hypogranular neutrophils ... transformation to AML ... blood count with differential ... progression to AML ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
ovarian tumors, lung cancers ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... Gap #ProteinGap #differential ... #diagnosis #hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
clonal evolution to acute ... myeloid leukemia ... (AML). ... cytopenias and AML ... #algorithm #hematology