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diagnosis workup anemia bleeding causes hemolytic hodgkins leukemoid lymphoma management nonpalpable oncology palpable purpura testing thrombocytosis thromboticthrombocytopenicpurpura ttp wbc
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential ... Diagnosis Algorithm ... Symptoms: B-symptoms, bruising ... anemia, ↑ MCV, ↑/↓ platelets ... #hematology #WBC
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
- Differential ... Thrombocytopenia ... Sequestration Disordered Platelet ... • Steroids • Vasculitis ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Count - Differential ... → Refer to hematology ... blood loss, Acute hemolysis ... , Vasculitides, ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... Pigmented Purpuric Dermatosis ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... with or without platelet ... Schistocytes, thrombocytopenia ... cardiac valve, vasculitis ... #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Platelet count ... WBC count and differential ... - Shows a mild leukocytosis ... Diagnosis #Workup #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... -95% of cases) Classification ... - Low Hb and platelets ... Immunohistochemical studies (to differentiate ... #hematology #oncology
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