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coagulation lupus activation bleeding bruising comparison dic disseminated druginduced hemophilia hemostasis intravascular macrophage mas mixing studies summary syndrome table vasculitis
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Abnormal APTT Step ... of Prolonged APTT ... #APTT #prolonged ... #diagnosis #hematology ... #studies #PTT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... PT and aPTT 1. ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #PT #aPTT #Prolonged ... hematology #coagulation
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... of SLE • Evolution ... #Diagnosis #Management ... #Summary #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
PT/PTT • Low ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... #causes #treatment ... #management #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... established disease) • aPTT ... mixing study (aPTT ... PT/INR & von Willebrand ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Lupus Erythematosus ... of SLE • Evolution ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
[SLE], AOSD) • ... Hypofibrinogenemia • ↑ PT ... ↑ PTT • ↑ Fibrin ... #Management #Hematology ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... diseases, such as SLE ... ischemia • Skin: Erythematous ... often causes arthritis ... #Diagnosis #Rheumatology
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