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diagnosis management antibodies antinuclear dermatology lupus patterns purpura thrombocytopenia activation algorithm alopecia antibody antineutrophil aortitis autoimmune cerebritis champs clues cns
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
lupus erythematosus ... in drug-induced SLE ... • Sjögren syndrome ... Jcortesizaguirr #ANA ... antibodies #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Syndrome (SS), ... (SLE), Systemic ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... small vessels - ANCA-associated ... - systemic ... lupus erythematosus ... #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Nodosa (PAN), ANCA ... lupus erythematosus ... (SLE), Sarcoidosis ... #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Vasculitis: + MPO-ANCA ... , and SLE) • Urinalysis ... #rheumatology # ... classification
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... ASA) • Renal Disease ... #Bruising #Differential ... #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... #classification ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Syndrome (SS), ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... #Diagnosis #Rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Pigmented Purpuric Dermatosis ... Cryoglobulinemia (MIXED) • ANCA ... #Diagnosis #hematology ... #rheumatology #
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