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diagnosis erythematosus antinuclear vasculitis abnormal coagulation management patterns prolonged pt workup allergy anca antibody antineutrophil aortitis arthritis autoantibodies champs clues
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
(SLE), Systemic ... #Antinuclear #Antibodies ... #ANA #patterns ... #rheumatology #diagnosis ... #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Highly specific antibodies ... #Criteria #SLE ... #Systemic #Lupus ... Erythematosus #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Systemic ... (SLE), Systemic ... #rheumatology #diagnosis ... #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies ... Diagnosis and Lupus ... #Systemic #Lupus ... #rheumatology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... and the aPTT are ... antiphospholipid antibodies ... associated with systemic ... #hematology #coagulation
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... ) • Systemic sclerosis ... Jcortesizaguirr #ANA ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Kikuchi disease • Type-I ... #Systemic #Lupus ... Erythematosus #Diagnosis #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... Mnemonic #diagnosis #differential ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... : INR/PT, aPTT(liver ... (e.g., SLE), anti-phospholipid ... antibodies, Quantitative ... #Workup #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... antiphospholipid antibodies ... associated with systemic ... #diagnosis #differential ... #hematology #coagulation
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