11 results
cutaneous cryoglobulins dermatologic dermpath glomerulonephritis granulomatosis lesions manifestations monoclonal nonpalpable oncology palpable paraproteinemias pathology polyangiitis purpura rapidly rash rpgn semiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm ... #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Urticarial/LCV) - Cryoglobulinemic ... ANCA Associated: ... #skin #dermatology ... #rheumatology # ... differential #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Ig A vasculitis ... HCV, HBV Not Vasculitis ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Vasculitis: + MPO-ANCA ... differential #diagnosis ... #rheumatology # ... classification
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
Vasculitis There ... pathologically or clinically ... #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... (5%): PAN > GPA ... #dermpath #dermatology ... signs #lesions #diagnosis ... #clinical #manifestations
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- GPA, EGPA, microscopic ... • IgA vasculitis ... • Vasculitis ... #rheumatology # ... vasculitis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Pauci-immune vasculitis ... Diagnosis: Vasculitis ... #dermatology #rash ... #diagnosis #rheumatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Diagnosis Algorithm ... insufficiency • Vasculitis ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... tract, and often causes ... + MPO) Cryoglobulinemic ... Diagnosis #Rheumatology
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