10 results
Beta Lactam Antibiotic Classification

UPDATE 10/2018: meropenem-vaborbactam added

Penicillins, Cephalosporins, Monobactam, Carbapenems 

 - Dr. David Serota @serotavirus

#BetaLactams
Beta Lactam Antibiotic ... Classification ... Penicillins, Cephalosporins ... #Classification ... #Pharmacology #
Cephalosporin Antibiotic Generations - Mnemonic
1st Generation "FA/PHA": CEFAZOLIN, CEFADROXIL, CEPHALEXIN, CEPHALOTHIN, CEPHAPIRIN, CEPHRADINE
2nd Generation "Everything Else":
Cephalosporin Antibiotic ... CEFTOBIPROLE #Cephalosporins ... #Antibiotics #Generations ... #Mnemonic #classification ... #pharmacology
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
Antibiotics and ... Macrolides #Antibiotics ... BloodBrain #Perfusion #CSF ... #Pharmacology # ... Classification #
Cephalosporin Antibiotics
 • First Generation: Cefazolin, Cefadroxil, Cephalexin
 • Second Generation: Cefuroxime sodium, Cefuroxime axetil
 •
Cephalosporin Antibiotics ... Generation: Cefepime #Cephalosporin ... #Antibiotics #comparison ... #pharmacology # ... classification
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
like PCN and cephalosporins ... ) - Switch to cephalosporin ... in presence of PCNs ... or cephalosporins ... Proteins #AMR #PBP #pharmacology
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Antibiotic Classification ... Penicillins Cephalosporins ... : Rifampin #Antibiotic ... #Classification ... #Pharmacology #
Cephalosporins 
Cephalosporins are bactericidal beta-lactam antibiotics derived from the fungus Acremonlum— they disrupt peptidoglycan formation in
Cephalosporins ... bactericidal beta-lactam antibiotics ... #Generations #Classification ... #pharmacology # ... Antibiotics
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
Antibiotic classification ... Antibiotics are ... include penicillins, cephalosporins ... #Antibiotics #pharmacology ... #classification
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Molecules • Ex: Antibiotic ... . penicillin & cephalosporin ... Syndrome, Contact Dermatitis ... Reactions #Types #Classification
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
CSF Penetration ... Despite the poor CSF ... compared to other antibiotic ... levels in the CSF ... InfectiousDiseases #Pharmacology