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differential hematology management dermatology classification monoclonal vasculitis infections leukemia mgus myelodysplastic neurology treatment workup abnormal adrenal ai algorithm anemia aplastic
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Neutrophilic dermatosis ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Pigmented Purpuric Dermatosis ... Gardner-Diamond syndrome ... #hematology #rheumatology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Infectious Causes of Adrenal Insufficiency Anatomical distribution of vessels to the adrenal makes the gland prone to
disseminated microbial disease ... Waterhouse-Friderichsen syndrome ... neoformans, Blastomyces dermatitidis ... #differential #diagnosis ... endocrinology #infectiousdiseases
Waterborne Infections - Differential Diagnosis Framework Infections that can be acquired from fresh water, brackish water, sea
- Differential Diagnosis ... Hemolytic Uremic Syndrome ... is biphasic • Clinical ... - And, in rare cases ... #InfectiousDiseases
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... • Neutrophilic dermatosis ... Sneddon-Wilkinson disease ... #Differential #Diagnosis ... #Oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... capillary leak syndrome ... Ig deposition disease ... #hematology #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... with systemic disease ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Differential Diagnosis ... • Goodpasture syndrome ... #rheumatology
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