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algorithm clinical cutaneous generalized rheumatology secondary syndrome systemic classification dermpath granulomatosis hodgkins lesions management monoclonal nonpalpable palpable paraproteinemias pathology polyangiitis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Neutrophilic dermatosis ... #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis ... : • Lymphoma ... Throbocythemia • Myelodisplastic ... #generalized #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... #Dermatologic ... #dermatology #rash ... #diagnosis #rheumatology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... (5%): PAN > GPA ... #dermpath #dermatology ... signs #lesions #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Pigmented Purpuric Dermatosis ... #Diagnosis #hematology ... #nonpalpable #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... : • Lymphoma ... Throbocythemia • Myelodisplastic ... #generalized #dermatology ... #causes
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... • Heavy Chain disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Anemia • Pruritis ... Workup: • Full ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Causes: - Idiopathic ... (malignancy), lymphoma ... , breast CA - Hematologic ... #dermatology #oncology
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