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algorithm liver injury rheumatology workup anemia bile brue cardiology cholangitis cirrhosis dermatology dili druginduced duct event extravascular hemolysis hemolytic hepatitis
Liver Mass Differential Diagnosis Solid: • Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules •
Polycystic liver disease ... , Biliary cysts ... SCC Infectious: ... #Diagnosis #hepatology ... #Radiology
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm Cardiac: • Congenital Heart Disease •
Congenital Heart Disease ... Arrhythmia • Cardiomyopathy ... age-dependent) Infectious ... Respiratory Tract Infection ... Tract Infection
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia • Primary ... Myelofibrosis Infectious ... • Rheumatic disorders ... • Celiac disease ... #Causes #Hematology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Diagnosis Algorithm ... Hemochromatosis • Wilson's Disease ... Pericarditis Infectious ... Biliary Cirrhosis ... #Causes #Hepatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... SLE) - Viral infections ... APLS • Acute Infectious ... : Schamberg Disease ... #Diagnosis #hematology
Right-Sided Heart Failure - Differential Diagnosis Algorithm Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
Obstructive Pulmonary Disease ... • Diffuse Lung Disease ... • Chronic Lung Infection ... Veno-Occlusive Disease ... #Cardiology #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
cold agglutin disease ... Mycoplasma pneumoniae infection ... e.g. sickle cell disease ... spherocytosis) • Infections ... diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... but elevated as disease ... fungal, viral infections ... , IgG4 related disease ... #workup #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
procedures - Infection ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... hematologic disorder ... #Workup #hematology
Bile Duct Paucity - Differential Diagnosis • Genetic: Alagille syndrome, Trisomy 21, Williams syndrome, Peroxisomal disorders
Diagnosis • Genetic ... Panhypopituitarism • Infections ... Graft-versus-host disease ... atresia (late finding ... #hepatology #Differential
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